Sleep Deprivation in the Rat: III. Total Sleep Deprivation

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Sleep deprivation in the rat: III. Total sleep deprivation.

Ten rats were subjected to total sleep deprivation (TSD) by the disk apparatus. All TSD rats died or were sacrificed when death seemed imminent within 11-32 days. No anatomical cause of death was identified. All TSD rats showed a debilitated appearance, lesions on their tails and paws, and weight loss in spite of increased food intake. Their yoked control (TSC) rats remained healthy. Since dehy...

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ژورنال

عنوان ژورنال: Sleep

سال: 1989

ISSN: 0161-8105,1550-9109

DOI: 10.1093/sleep/12.1.13